Biosafety cabinet (biological safety cabinet.BSC) is a box type air purification negative pressure safety device which can prevent aerosol escape in some dangerous or unknown biological particles during experimental operation and treatment. It is widely used in microbiology, biomedicine, genetic engineering, biological products and other fields of scientific research, teaching, clinical testing and production, and is the most basic safety protection equipment in the first class protective barrier in laboratory biosafety

The working principle of the biosafety cabinet is to pump the air out of the cabinet to keep the negative pressure in the cabinet and protect the staff through vertical air flow. The air in the cabinet also needs to be filtered by HEPA filters to protect the environment.